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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CP All Species: 26.67
Human Site: T139 Identified Species: 73.33
UniProt: P00450 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00450 NP_000087.1 1065 122205 T139 G A I Y P D N T T D F Q R A D
Chimpanzee Pan troglodytes XP_508699 1298 146493 T285 G A L Y P D G T S G R N K N D
Rhesus Macaque Macaca mulatta XP_001109373 1069 122627 T139 G A I Y P D N T T D F Q K A D
Dog Lupus familis XP_534301 1065 122544 T139 G A I Y P D N T I G S H K A D
Cat Felis silvestris
Mouse Mus musculus Q61147 1061 121133 T139 G A V Y P D N T T D F Q R A D
Rat Rattus norvegicus P13635 1059 120822 T139 G A I Y P D N T T D F Q R A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508540 962 108933 V104 F V V M F S V V D E N L S W Y
Chicken Gallus gallus XP_001235149 1079 123193 T141 G A F Y P D N T K G F E K R D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571877 1087 124540 S142 G A L Y P D S S E K V E K H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.7 96.6 84.3 N.A. 83.2 82.1 N.A. 66.1 59.8 N.A. 54.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 57.4 97.7 91.6 N.A. 90.8 89.3 N.A. 75.9 75.4 N.A. 71.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 93.3 66.6 N.A. 93.3 100 N.A. 0 60 N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 66.6 100 73.3 N.A. 100 100 N.A. 13.3 73.3 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 89 0 0 0 0 0 0 0 0 0 0 0 56 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 89 0 0 12 45 0 0 0 0 89 % D
% Glu: 0 0 0 0 0 0 0 0 12 12 0 23 0 0 0 % E
% Phe: 12 0 12 0 12 0 0 0 0 0 56 0 0 0 0 % F
% Gly: 89 0 0 0 0 0 12 0 0 34 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 12 0 12 0 % H
% Ile: 0 0 45 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 12 12 0 0 56 0 0 % K
% Leu: 0 0 23 0 0 0 0 0 0 0 0 12 0 0 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 67 0 0 0 12 12 0 12 0 % N
% Pro: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 12 0 34 12 0 % R
% Ser: 0 0 0 0 0 12 12 12 12 0 12 0 12 0 0 % S
% Thr: 0 0 0 0 0 0 0 78 45 0 0 0 0 0 0 % T
% Val: 0 12 23 0 0 0 12 12 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % W
% Tyr: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _